Some of these studies are incredible! Check it out…..Carnosine has been proven to reduce or completely prevent cell damage caused by beta-amyloid (AKA amyloid-beta, amyloid ß-protein, and Aß), one of the prime suspected protein risk factors for Alzheimer’s. Carnosine lowers elevated blood sugar levels, improves insulin production and sensitivity, and promotes the loss of weight and body fat. And if this were not enough, studies have shown that people who are diabetic or even pre-diabetic have lower-than-normal carnosine levels in both their muscle and brain cells. L-carnosine enhanced wound healing significantly. In addition, wound tissue analysis showed increased expression of growth factors and cytokines genes involved in wound healing. The protective effects of carnosine in mouse bone marrow cells against damage to their genetic structure caused by the chemotherapy drug cyclophosphamide.
PROTEIN MODIFICATION FOR LONGEVITY
As I said, aging is associated with damage to cellular proteins. But carnosine protects cellular proteins from damage in at least two ways.
Carnosine bonds with the carbonyl (or aldehyde) groups that if left alone will attack and bind with proteins.
It works as an antioxidant to prevent the formation of oxidized sugars, also called Advanced Glycosylation End-products or AGEs for short. That’s really the caramelization thing that I mentioned earlier. The bottom line here is that the less AGEs, in your body, the younger you are.
Both of these processes have important implications for anti-aging therapy. The key is that carnosine not only prevents damaging cross-links from forming, it eliminates cross-links that have previously formed in proteins, thus restoring normal membrane function in cells.
L-carnosine (AKA carnosine), a naturally occurring combination of two amino acids, was discovered in Russia in the early 1900s. Because much of the pioneering research was done in Russia, it was largely unavailable to the rest of the world until a number of studies and experiments in other parts of the world began verifying those studies — and more.
Most notably, there were a series of astonishing experiments done in Australia that proved that carnosine rejuvenates cells as they approach senescence (the stage just before death where a cell is still alive, but essentially non-functional). The studies showed that cells cultured with carnosine lived longer and retained their youthful appearance and growth patterns.
What’s probably the most exciting result of the studies is that it was discovered that carnosine can actually reverse the signs of aging in senescent cells